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Two Tower Pl
South San Francisco, CA 94080 Paradise Valley

Rate Upon Request

Office For Lease  •  11,480+ SF

Property Details

  • Property Type Office
  • Year Built 2019
  • Total Building Size 394,000 SF
  • Tenancy Multiple
  • Building Class A
50 Transit Score
40 Walk Score

4 Spaces Available

Name Space Use Size Rent Details
4th Floor Ste Flex 19,608 SF Rate Upon Request 
The 4th Floor features a biology lab with dedicated lab support space, a 6-foot fume hood, and house gases including vacuum and CDA. The layout includes a café/break room, four conference rooms, seven private offices, a mother’s/wellness room, IT room, reception area, huddle space, and open office seating, supporting both research and administrative functions.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
9th Floor Ste Flex 11,480 SF Rate Upon Request 
The 9th Floor is configured with biology, tissue culture, pre-PCR, and post-PCR laboratory areas supported by dedicated lab support rooms. The suite includes a 6-foot fume hood, house gases, a café/break room, conference room, three private offices, two phone rooms, copy/print area, IT room, collaboration seating, and open office space.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
12nd Floor Ste Flex 19,861 SF Rate Upon Request 
The 12th Floor offers a biology laboratory with analytical lab areas, house gases, and two fume hoods. The space includes two conference rooms, twenty-seven private offices, a phone room, mother’s/wellness room, IT room, reception area, break room, open office workspace, and dedicated laboratory support areas designed to accommodate research and operational teams.

  • Date available: Jan 2027
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
13rd Floor Ste Flex 12,555 SF Rate Upon Request 
The 13th Floor combines lab and lab support space with a flexible office component. The layout includes a café/break room, conference room, three private offices, open office areas, storage and telecom support rooms, and laboratory workspace arranged to support research activities alongside collaborative and administrative functions.

  • Date available: Dec 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet

Description 

Two Tower Place is a life science property in South San Francisco offering laboratory and office space across multiple floors. Building infrastructure includes laboratory exhaust systems, laboratory waste and vent risers, supplemental cooling, standby power capabilities, freight and passenger elevators, and building systems designed to support laboratory operations. On-site amenities include conferencing facilities, fitness center, dining options, tenant lounge areas, structured parking, and shipping/receiving support. The property is located near San Francisco International Airport with access to Downtown San Francisco, Silicon Valley, and regional transit connections.

Highlights

Purpose-built life science environment dedicated exclusively to research users.
Existing laboratory infrastructure supports accelerated occupancy timelines.
Multiple full-floor opportunities with laboratory and office improvements.
Extensive building systems include standby power and supplemental cooling.

Property Flyers

Amenities

  • Partitioned Offices
  • Air Conditioning

Public Transportation

Commuter RailDriveWalkDistance
4 min - 1.5 mi
7 min - 3.5 mi
AirportDriveWalkDistance
San Francisco International 9 min - 5.0 mi
Metro Oakland International 42 min - 27.9 mi
Norman Y Mineta San Jose International 46 min - 36.7 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 50
Type: Surface
Included in Rent: Yes
Dino Perazzo 650-577-2997 CBRE, Inc.
Dino Perazzo 650-577-2997 CBRE, Inc.