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6400 Overseas Hwy
Marathon, FL 33050

$3,469 USD/MO

Medical For Lease  •  2,191 SF

Property Details

  • Property Type Medical
  • Year Built 1981
  • Total Building Size 4,383 SF
  • Tenancy Multiple
  • Building Class C
  • Zoning Commercial
0 Transit Score
52 Walk Score

1 Space Available

Name Space Use Size Rent Details
1st Floor Ste Downstairs Office Office 2,191 SF $19.00 USD/SF/YR
Prime US-1 Commercial Space for Lease – 2,400 sq. ft. First Floor | Marathon, FL

Now available for lease in Marathon, Florida: a spacious 2,400 sq. ft. ground-floor commercial unit in a freestanding building with 100 feet of US-1 highway frontage—offering excellent visibility and signage opportunities. Located on a 17,519 sq. ft. lot, this property provides ample off-street parking, beautiful tropical landscaping, and convenient access for customers and deliveries.

The entire first floor is available and includes:
– Two restrooms
– Welcoming waiting area
– Front desk/reception space
– Two open common areas
– Seven private rooms/offices
– Oversized garage-style storage room with a separate entrance and kitchenette—perfect for storing inventory, receiving shipments, or converting into a breakroom, display room, or additional workspace
– Multiple built-in storage closets

Previously home to a long-standing optometrist’s office, this flexible layout is ideal for a medical or dental practice, real estate firm, law office, wellness spa, or professional services looking to establish themselves in the heart of the Florida Keys.

Available September 1, 2025
?? Monthly Lease: $3,800
?? Additional Fee: $150month (water & trash) 
?? Tenant pays all other utilities

Landlord-friendly lease terms!
To support your business startup or relocation, the owner is waiving the traditional last month and security deposit requirements. This allows tenants to use their funds toward custom build-outs—including updated flooring, bathroom renovations, or paint to reflect their brand and style.

Lease terms available for 1, 2, 3, or 5 years. The building has been recently upgraded, including extensive improvements to the structure and surrounding landscaping.

Take advantage of this rare opportunity to grow your business in Marathon, FL—one of the most vibrant and desirable communities in the Florida Keys.

Owner is a licensed Florida Keys Real Estate Agent.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: Plus All Utilities
  • Space Type: Relet

Description

REDUCED!!! Prime US-1 Commercial Space for Lease – 2,400 sq. ft. First Floor | Marathon, FL

Now available for lease in Marathon, Florida: a spacious 2,400 sq. ft. ground-floor commercial unit in a freestanding building with 100 feet of US-1 highway frontage—offering excellent visibility and signage opportunities. Located on a 17,519 sq. ft. lot, this property provides ample off-street parking, beautiful tropical landscaping, and convenient access for customers and deliveries.

The entire first floor is available and includes:
– Two restrooms
– Welcoming waiting area
– Front desk/reception space
– Two open common areas
– Seven private rooms/offices
– Oversized garage-style storage room with a separate entrance and kitchenette—perfect for storing inventory, receiving shipments, or converting into a breakroom, display room, or additional workspace
– Multiple built-in storage closets

Previously home to a long-standing optometrist’s office, this flexible layout is ideal for a medical or dental practice, real estate firm, law office, wellness spa, or professional services looking to establish themselves in the heart of the Florida Keys.

Available Now
Monthly Lease: $3,800
Additional Fee: $150/month (water & trash) 
Tenant pays all other utilities

Landlord-friendly lease terms!
To support your business startup or relocation, the owner is waiving the traditional last month and security deposit requirements. This allows tenants to use their funds toward custom build-outs—including updated flooring, bathroom renovations, or paint to reflect their brand and style.

Lease terms available for 1, 2, 3, or 5 years. The building has been recently upgraded, including extensive improvements to the structure and surrounding landscaping.

Take advantage of this rare opportunity to grow your business in Marathon, FL—one of the most vibrant and desirable communities in the Florida Keys.

Owner is a licensed Florida Keys Real Estate Agent.

Highlights

100 feet of US-1 highway frontage—offering excellent visibility and signage opportunities!
Large 17,519 sq. ft. lot with ample off-street parking, beautiful tropical landscaping, and convenient access for customers and deliveries!
Oversized garage-style storage room!

Property Flyers

Amenities

  • Storage Space
  • Air Conditioning

Major Tenants

Tenant SF Occupied Lease End Date
Cruz In The Keys Construction
Massage Parlour
Nails Salon

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 20
Type: Surface
Included in Rent: Yes
Eva Polizze 305-900-7675 Xcellence Realty
Eva Polizze 305-900-7675 Xcellence Realty