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5420 West Loop S
Bellaire, TX 77401

Rate Upon Request

Medical For Lease • 1,149+ SF

Property Details

Property Type Medical
Year Built 2007
Total Building Size 102,452 SF
Tenancy Multiple
Building Class A
Zoning N/Ap

49 Transit Score

65 Walk Score

7 Spaces Available

Name	Space Use	Size	Rent
1st Floor Ste 1200	Medical Office	2,599 SF	Rate Upon Request
Date available: Jan 2027 Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
1st Floor Ste 1500	Medical Office	1,747 SF	Rate Upon Request
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
1st Floor Ste 1700	Medical Office	2,631 SF	Rate Upon Request
Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking Date available: Apr 2026 Lease term: Negotiable Service type: To Be Determined Space Type: New
1st Floor Ste 1800	Medical Office	1,149 SF	Rate Upon Request
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
3rd Floor Ste 3500	Medical Office	3,238 SF	Rate Upon Request
Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
4th Floor Ste 4100	Medical Office	9,097 SF	Rate Upon Request
Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet In Contiguous block: 13,258 SF
4th Floor Ste 4500	Medical Office	4,161 SF	Rate Upon Request
Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet In Contiguous block: 13,258 SF

Description

5420 West Loop South offers a premier medical office opportunity within the Bellaire submarket. This Class A, 4-story medical office building, was completed in 2008 and features 102,452 SF of rentable building area (RBA). Centrally located and directly connected to the Memorial Hermann Orthopedic & Spine Hospital, the property provides convenient access to I-610 and I-69, with a quick 17-minute commute to Texas Medical Center. 

The building offers on-site security and property management, covered patient drop-off, a gurney-accessible elevator, renovated common areas and abundant garage parking. With opportunities for monument and building signage, generous tenant improvement allowances, and flexible lease terms, 5420 West Loop S is an ideal location for medical practices seeking a high-quality, accessible, and well-amenitized space.

                
                    Highlights
                
                                Excellent location
                            
                                Newly renovated common areas
                            
                                On-site security and property management
                            
                                Covered patient drop-off
                            
                                Abundant garage parking
                            
                                No use restrictions

Property Flyers

5420 West Loop South Flyer 1-2-2026

Amenities

Bus Line
Signage
Skyway
Monument Signage

Public Transportation

Commuter Rail	Drive	Walk	Distance
	16 min	-	8.6 mi
Airport	Drive	Walk	Distance
William P Hobby	30 min	-	17.9 mi
George Bush Intcntl/Houston	36 min	-	27.8 mi

Parking Details

Parking Available:	Yes
Reserved:	No
Spaces Provided:	5
Type:	Surface
Included in Rent:	Yes

Angela Barber 832-455-6945 CBRE

5420 West Loop S Bellaire, TX 77401