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50 Tanforan Ave
South San Francisco, CA 94080 Lindenville

Rate Upon Request

Unknown For Lease • 48,685+ SF

Property Details

Property Type Unknown
Year Built 2025

0 Transit Score

64 Walk Score

12 Spaces Available

Name	Space Use	Size	Rent
1st Floor Ste	Flex	48,685 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
1st Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF
2nd Floor Ste	Flex	64,431 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
2nd Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF
3rd Floor Ste	Flex	64,965 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
3rd Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF
4th Floor Ste	Flex	64,901 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
4th Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF
5th Floor Ste	Flex	64,901 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
5th Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF
6th Floor Ste	Flex	64,860 SF	Rate Upon Request
Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Optional floor plates with a lab build-out or tech build-out. The lab plans typically span an approximate 55,000-square-foot floor plate and comprise 50% lab and 50% office. A tech plan will comprise a 55,000-square-foot floor plate with 292 workstations, 21 private offices, and two large conference rooms. Date available: Now Lease term: Negotiable Service type: To Be Determined Space Type: Relet In Contiguous block: 372,743 SF
6th Floor Ste	Flex	57,500 SF	Rate Upon Request
Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance of Caltrain. Southline will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life balance in one of the most exciting developing neighborhoods in the Bay Area. Designed to LEED Gold and Fitwel 2-Star Certification Standards. Date available: Dec 2027 Lease term: Negotiable Service type: To Be Determined Space Type: New In Contiguous block: 345,000 SF

Description

Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance to Caltrain. The campus will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life experience in one of the most exciting developing neighborhoods in the Bay Area.

With modern innovation in mind, Southline offers expansive, flexible floor plates ranging from 50,000 to 100,000 square feet of office space. Up to 65,000 square feet is dedicated to life science use. Office ceiling heights of 16 feet on the ground floor and 14 feet on the upper levels provide a spacious, open feel. Life science areas feature 16 to 18 feet of clearance, accommodating high-capacity storage and specialized equipment. Generous 30- to 33-foot column spacing, a strong live load capacity of approximately 125 pounds per square foot, and 8,000 MIPs ensure the project is equipped to support even the most demanding operations.

Designed for innovation, inside out, Southline has curated amenities, restaurants, and retail that give big ideas space to grow, offering structure for deep thinking and space for spontaneity. The mass timber dedicated amenity building brings to the campus a fitness and wellness center, a coffee bar and grab-n-go food options, a conference center, outdoor seating areas, a well-appointed walking trail, a fruit and veggie garden, a campus Caltrain shuttle, a designated rideshare area, and a bike barn with a repair desk. A beer garden, fire pits, food truck court, outdoor collaboration areas, games and activities, and the Southline Commons (a 2-acre open space) are included in Phase 2, coming soon.

Situated at the intersection of 101, 380, and 280, where BART and Caltrain converge and just minutes from San Francisco International Airport (SFO), the entire Bay Area is as accessible as it has ever been at Southline. Over 2,300 housing units are within a short walk of this project. All this and more provides the opportunity to recruit and retain from everywhere.

Southline is in the center of Lindenville, a burgeoning, mixed-use neighborhood that soon will become an employment hub and the cultural heart of South San Francisco. In addition, it is across the street from a planned new 400,000 square foot retail village at Tanforan, including restaurants, cafes, Target, and a cinema. This growing area will offer a walkable live/work community, creating opportunities to shape South San Francisco's next chapter.

South San Francisco has a rich history of pioneering industry and seamlessly bridges the innovative spirit of San Francisco with the technological prowess of Silicon Valley. At Southline, inspiration is tradition, and the Industrial City will give birth to the next phase of creative thinkers, disruptors, and pioneers fueled by the energy of its surroundings.

                
                    Highlights
                
                                Southline is a 31-acre purpose-built science and technology development in South San Francisco, directly adjacent to BART and walkable to Caltrain.
                            
                                Amenities galore: fitness & wellness center, coffee bar & grab-n-go options, conference center, outdoor seating, and well-appointed walking trail.
                            
                                Featuring 2.8 million SF of Class A office and life science space, offering an authentic work-life experience. 
                            
                                At the intersection of 101 / 380 / 280, walkable to BART and Caltrain, and minutes from SFO, the entire Bay Area is as accessible as it has ever been.
                            
                                Now leasing Phase 1A, with 375,000 SF across six stories available and ready for tenant improvements, adjoined with parking and amenities. 
                            
                                Adjacent to two shopping centers with 40+ restaurants, over 100 shops and services, and within walking distance to 2,300 new residential units.

Property Flyers

20 Southline Ave

Public Transportation

Commuter Rail	Drive	Walk	Distance
	3 min	15 min	0.8 mi
South San Francisco (Caltrain - Caltrain (Caltrain))	5 min	-	1.8 mi
Transit/Subway	Drive	Walk	Distance
San Bruno Station (Dublin/Pleasanton - Millbrae - Bay Area Rapid Transit (BART), Pittsburg/Bay Point - San Francisco International - Bay Area Rapid Transit (BART), Richmond - Millbrae - Bay Area Rapid Transit (BART))	5 min	6 min	0.3 mi
Airport	Drive	Walk	Distance
San Francisco International	9 min	-	3.6 mi
Metro Oakland International	44 min	-	29.5 mi
Norman Y Mineta San Jose International	46 min	-	35.2 mi

Dan Matteucci 650-374-2679 Newmark

50 Tanforan Ave South San Francisco, CA 94080 Lindenville