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50 Main St
Hempstead, NY 11550

$6,667 USD/MO

Medical For Lease  •  2,000 SF

Property Details

  • Property Type Medical
  • Year Built 1930
  • Total Building Size 4,145 SF
  • Tenancy Multiple
  • Building Class B
  • Zoning commercial
70 Transit Score
80 Walk Score

1 Space Available

Name Space Use Size Rent Details
1st Floor Ste Medical Office 2,000 SF $40.00 USD/SF/YR
Outstanding ground-floor commercial space available for lease in the heart of downtown Hempstead, on Main Street between Fulton Street and Front Street. The space offers approximately 2,000 sq. ft. of street-level space, plus an additional ±300 sq. ft. of basement storage, and is currently built out as a polished professional office — featuring a welcoming reception and client waiting area, multiple private offices, a conference room, an open work area, a kitchenette, and a private bathroom. The space has central HVAC, and the building's electrical service has just been upgraded. The space is wired for internet and Wi-Fi ready. The current build-out can be modified by the tenant to suit its needs. The space is delivered unfurnished.

Ideally located in a high-traffic, high-visibility commercial district, the space sits beside a municipal parking lot on the adjacent corner and is just two blocks from the Hempstead LIRR station, the regional bus terminal, and the courthouse. Suitable for medical, professional/office, or retail use, with a negotiable duration of the lease term.

  • Date available: Aug 2026
  • Lease term: Negotiable
  • Service type: Plus All Utilities
  • Space Type: Relet

Description

This is an excellent opportunity for a medical practice, professional office, retail business, or storefront in a high-visibility, high-traffic downtown setting. Prime ground-floor commercial space in the heart of downtown Hempstead — one of Nassau County's busiest, most transit-rich commercial corridors. This versatile approx. 2,000 SF unit offers a flexible layout with open space plus three private offices, and all interior walls and partitions can be easily removed to create a build-out tailored to your business.   
Partially tiled and partially carpeted
Central HVAC system (heat and air conditioning)
Completely renovated four years ago
Building electrical service upgraded this year
Lease term negotiable
Unbeatable Downtown Location:
Two blocks from the Hempstead Transit Center — the largest bus hub in Nassau County, served by roughly 17–19 NICE bus routes plus Greyhound intercity service
Same two blocks to the Long Island Rail Road Hempstead Station (Hempstead Branch terminal), with direct service to Jamaica and Penn Station, Grand Central Station
Steps from the Nassau County courthouse, banks, and a dense mix of retail and dining
Large municipal parking lot on the corner — significant public parking capacity in the immediate area
Exceptional walk-up foot traffic from daily commuters and downtown workers

Contact us today to schedule a showing 212-760-1000 (text/call). rmjglobainc@aol.com

Highlights

Daytime foot traffic, 2 blocks from major Bus Terminal, Long Island Rail Road (LIRR) and courthouse. Municipal car parking lot is on the corner
Lots of natural light through large front windows.Central HVAC system (heat and air conditioning)
Flexible floor plan: open area combined with three private offices. Interior walls/partitions easily removable for fully custom layouts.

Amenities

  • 24 Hour Access
  • Conferencing Facility
  • Signage
  • Reception
  • Storage Space
  • Air Conditioning
  • Smoke Detector
  • Awning

Public Transportation

Commuter RailDriveWalkDistance
Hempstead Station (Hempstead Branch - Long Island Rail Road) 2 min 8 min 0.4 mi
West Hempstead Station (West Hempstead Branch - Long Island Rail Road) 3 min - 1.1 mi
Transit/SubwayDriveWalkDistance
Hempstead Station (Hempstead Branch - Long Island Rail Road) 2 min 8 min 0.4 mi
AirportDriveWalkDistance
John F Kennedy International 21 min - 13.0 mi
LaGuardia 30 min - 16.8 mi
Westchester County 59 min - 38.3 mi
Tim Mirzayev 212-760-1000 RMJ Global Inc.
Tim Mirzayev 212-760-1000 RMJ Global Inc.