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486 N Patterson Ave
Winston-Salem, NC 27101 Innovation Quarter

Rate Upon Request

Office For Lease  •  3,306 SF

Property Details

  • Property Type Office
  • Year Built 2018
  • Total Building Size 110,800 SF
  • Tenancy Multiple
  • Building Class A
  • Zoning CI
30 Transit Score
70 Walk Score

1 Space Available

Name Space Use Size Rent Details
1st Floor Ste Office 3,306 SF Rate Upon Request 
±3,306 SF of cool industrial space with high ceilings, open floorplan, large windows, and ample storage
Great signage opportunities in front and on Coal Pit side
Co-located with high-traffic restaurants and bars
Fantastic location in Innovation Quarter; close to Bailey Park, Link IQ Apartments, Plant 64 Apartments, Wake Forest School of Medicine & School of Health Sciences, and future Atrium WF Eye Institute
Interior space features prep area, dishwashing station, grease trap, walk-in cooler, ample storage, multihead keg wall

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet

Description 

Innovation Quarter is a dynamic, mixed-use innovation district in the heart of downtown Winston-Salem - designed to bring research, business, education, and community into close proximity. Where ideas connect and collaboration follows.

Anchored by Wake Forest University School of Medicine, the district is home to more than 4,500 workers, 115 companies, and nearly 2,000 students. From biomedical science and clinical services to technology, data, and advanced materials, Innovation Quarter supports a diverse and growing community of thinkers, builders, and problem-solvers.

Spanning more than 2 million square feet of office, lab, and academic space, the district blends cutting-edge facilities with walkable streets, residential living, and curated amenities.
With direct access to greenway trails and a vibrant downtown, Innovation Quarter offers more than just workspace - it offers a connected, energized environment where ideas move faster and possibilities expand.

Highlights

Redeveloped RJ Reynolds power plant with 110,800 SF of mixed-use space in Innovation Quarter.
Adjacent to Bailey Park and steps from Wake Forest University Health Sciences campus.
Flexible office and retail configurations with access to onsite tenant amenities.
High ceilings, industrial character, and vibrant common areas foster collaboration.
LEED Gold-certified with modern infrastructure and sustainable design throughout.
Surrounded by dining, entertainment, and residential options in downtown Winston-Salem.

Property Flyers

Green Rating

LEED Gold

Major Tenants

Tenant SF Occupied Lease End Date
A Society 10/17/2023
Alma Mexicana
CliftonLarsonAllen, LLP 8/1/2025
Cugino Properties
Dram and Draught
F45 Training, Inc.
Fluree
Incendiary Brewing Company
McAdams
Smith Leonard Acct & Consultants

Public Transportation

AirportDriveWalkDistance
Piedmont Triad International 34 min - 20.7 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 32
Type: Surface
Included in Rent: Yes
Cindy Christopher 336-926-1411 Christopher Commercial
Cindy Christopher 336-926-1411 Christopher Commercial