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444 S Main St
Ann Arbor, MI 48104 Downtown Ann Arbor

$700 - $1,050 USD/MO

Office For Lease  •  300+ SF

Property Details

  • Property Type Office
  • Year Built 1901
  • Total Building Size 3,537 SF
  • Tenancy Multiple
  • Building Class B
  • Zoning C2B/R
70 Transit Score
80 Walk Score

3 Spaces Available

Name Space Use Size Rent Details
Ll Floor Ste 002 Office 350 SF $24.00 USD/SF/YR
Tenants benefit from an all-inclusive leasing structure, with Wi-Fi and utilities incorporated into the rent—simplifying operations and providing predictable occupancy costs. The building also offers a range of shared amenities that enhance day-to-day convenience and overall quality of experience. A kitchenette provides a comfortable space for breaks and informal collaboration, while on-site shower facilities and secure bicycle storage support active commuting and work-life balance.

Additional features include weekly professional cleaning of common areas, ensuring a consistently clean and well-maintained environment, as well as a modern HVAC system equipped with advanced air filtration capable of removing 99.9% of airborne bacteria and viruses—an important consideration for health-conscious professionals and their clients.

On-site parking is available for an additional cost, offering added convenience for both tenants and visitors in a highly sought-after downtown location where accessibility is key. Whether located on the first floor or on the lower level offering an ADA accessible space, each suite provides a unique opportunity to establish or grow your practice in a professional, well-supported environment.

  • Date available: May 2026
  • Lease term: 2 Years
  • Service type: Full Service Gross
  • Built out as: Professional Services
  • Space Type: New
1st Floor Ste 101 Office 300 SF $36.00 USD/SF/YR
Tenants benefit from an all-inclusive leasing structure, with Wi-Fi and utilities incorporated into the rent—simplifying operations and providing predictable occupancy costs. The building also offers a range of shared amenities that enhance day-to-day convenience and overall quality of experience. A kitchenette provides a comfortable space for breaks and informal collaboration, while on-site shower facilities and secure bicycle storage support active commuting and work-life balance.

Additional features include weekly professional cleaning of common areas, ensuring a consistently clean and well-maintained environment, as well as a modern HVAC system equipped with advanced air filtration capable of removing 99.9% of airborne bacteria and viruses—an important consideration for health-conscious professionals and their clients.

On-site parking is available for an additional cost, offering added convenience for both tenants and visitors in a highly sought-after downtown location where accessibility is key. Whether located on the first floor or on the lower level offering an ADA accessible space, each suite provides a unique opportunity to establish or grow your practice in a professional, well-supported environment.

  • Date available: May 2026
  • Lease term: 2 Years
  • Service type: Full Service Gross
  • Built out as: Professional Services
  • Space Type: New
1st Floor Ste 102 Office 350 SF $36.00 USD/SF/YR
Tenants benefit from an all-inclusive leasing structure, with Wi-Fi and utilities incorporated into the rent—simplifying operations and providing predictable occupancy costs. The building also offers a range of shared amenities that enhance day-to-day convenience and overall quality of experience. A kitchenette provides a comfortable space for breaks and informal collaboration, while on-site shower facilities and secure bicycle storage support active commuting and work-life balance.

Additional features include weekly professional cleaning of common areas, ensuring a consistently clean and well-maintained environment, as well as a modern HVAC system equipped with advanced air filtration capable of removing 99.9% of airborne bacteria and viruses—an important consideration for health-conscious professionals and their clients.

On-site parking is available for an additional cost, offering added convenience for both tenants and visitors in a highly sought-after downtown location where accessibility is key. Whether located on the first floor or on the lower level offering an ADA accessible space, each suite provides a unique opportunity to establish or grow your practice in a professional, well-supported environment.

  • Date available: May 2026
  • Lease term: 2 Years
  • Service type: Full Service Gross
  • Built out as: Professional Services
  • Space Type: New

Description

Position your practice in one of Ann Arbor’s most desirable and highly recognizable professional corridors. Located at 444 South Main Street, this well-maintained office building offers an exceptional opportunity for psychologists, therapists, social workers, and other professional service providers seeking a thoughtfully designed and welcoming environment for both clients and staff. Tenants appreciate the building’s boutique scale, which fosters a quiet and professional environment compared to larger, more impersonal office properties. The layout is particularly well-suited for individual practitioners or small group practices.

The property combines the charm and character of Ann Arbor’s historic downtown with the functionality and efficiency required by modern professional users. The interior layout has been carefully configured to support counseling and clinical uses, featuring multiple private offices designed for confidentiality and comfort. Sound attenuation between rooms enhances privacy, while warm finishes and natural light contribute to a calm, professional atmosphere ideal for patient-facing practices. Shared spaces are thoughtfully arranged to create a seamless experience, including comfortable and private waiting areas and kitchenette space.

Situated just steps from the vibrant Main Street district, the building benefits from immediate access to an abundance of restaurants, cafés, retail amenities, and public transportation, creating a highly convenient and attractive setting for clients and employees alike. Additional features include convenient on-site or nearby parking options, well-maintained common areas, and strong visibility along South Main Street—one of Ann Arbor’s primary north-south corridors. The property’s central location also provides quick access to the University of Michigan campus, surrounding residential neighborhoods, and major commuter routes, making it an ideal location for practitioners drawing clients from across town.

This is a rare opportunity to lease space in a highly sought-after downtown location with a proven track record as a hub for mental health and professional services. Whether you are establishing a new practice or expanding an existing one, 444 South Main Street offers a turnkey environment designed to support productivity, privacy, and client comfort.

Highlights

Purpose-Built for Therapy & Professional Use
Prime Downtown Ann Arbor Location
Professional, Boutique Office Environment

Property Flyers

Amenities

  • 24 Hour Access
  • Controlled Access
  • Air Conditioning

Public Transportation

Commuter RailDriveWalkDistance
Ann Arbor Amtrak Station (Wolverine - Amtrak) 3 min 19 min 1.0 mi
AirportDriveWalkDistance
Detroit Metro Wayne County 35 min - 26.3 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 5
Type: Surface
Included in Rent: Yes
Erik Majcher 734-780-7105 Atlantes
Erik Majcher 734-780-7105 Atlantes