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435 Grand Ave
South San Francisco, CA 94080 Downtown South San Francisco

$8,993 USD/MO

Medical For Lease • 3,997+ SF

Property Details

Property Type Medical
Year Built 1973
Total Building Size 7,995 SF
Tenancy Multiple
Building Class C
Zoning CL00C2

60 Transit Score

80 Walk Score

2 Spaces Available

Name	Space Use	Size	Rent
1st Floor Ste	Medical Office	3,997 SF	$27.00 USD/SF/YR
Date available: Now Lease term: Negotiable Service type: Triple Net Built out as: Standard Medical Space Type: Relet In Contiguous block: 7,994 SF
2nd Floor Ste	Medical Office	3,997 SF	$27.00 USD/SF/YR
Date available: Now Lease term: Negotiable Service type: Triple Net Built out as: Standard Medical Space Type: Relet In Contiguous block: 7,994 SF

Description

Prime Medical Office Opportunity
Exceptional opportunity to acquire a well-located medical office building in the heart of South San Francisco’s established commercial corridor. Positioned on high-visibility Grand Avenue, this property benefits from strong pedestrian traffic, nearby retail amenities, and convenient access to Highway 101, I-280, BART, and SFO.
The building offers a functional medical layout with reception area, private exam rooms, administrative offices, and support space. Ideal for owner-users seeking to control occupancy costs or investors looking to reposition or lease in a high-demand medical market.
Surrounded by established businesses, residential neighborhoods, and biotech campuses, this location provides strong patient accessibility and long-term upside.
A rare opportunity to secure medical office space in one of the Peninsula’s most supply-constrained submarkets.

Amenities

Security System
Wheelchair Accessible
Reception
Storage Space
Air Conditioning

Public Transportation

Commuter Rail	Drive	Walk	Distance
	2 min	11 min	0.5 mi
	5 min	-	2.2 mi
Airport	Drive	Walk	Distance
San Francisco International	9 min	-	4.1 mi
Metro Oakland International	42 min	-	28.6 mi
Norman Y Mineta San Jose International	44 min	-	35.7 mi

Stephen Marshall 650-455-1528 Christies International Real Estate

435 Grand Ave South San Francisco, CA 94080 Downtown South San Francisco