List Search

4300 Duncan Ave
Saint Louis, MO 63110 Central West End

Rate Upon Request

Office For Lease  •  9,438+ SF

Property Details

  • Property Type Office
  • Year Built 2008
  • Total Building Size 189,841 SF
  • Tenancy Multiple
  • Building Class A
  • Zoning Commercial
59 Transit Score
73 Walk Score

2 Spaces Available

Name Space Use Size Rent Details
2nd Floor Ste 204 Office 9,438 SF Rate Upon Request
  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
4th Floor Ste 400 Office 36,122 SF Rate Upon Request 
- Top floor vacancy
- Full floor opportunity
- Excellent existing conditions
- 31 private offices and an IT room
- Building signage opportunity
- Available 5/1/2026

  • Date available: May 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet

Description 

Architecturally striking and built to Fortune 500 standards, 4300 Duncan is a future-forward workplace with technology and collaboration at its core. Infused with equal parts productivity and lifestyle, 4300 Duncan is situated at the center of the  Cortex Innovation District; a gravitational hub for top global talent. 

Cortex is a vibrant, 200-acre hub of business, innovation, and technology integrated into St. Louis’ historic Central West End and Forest Park Southeast neighborhoods, surrounded by nationally-ranked universities and medical centers and abundant cultural and recreational assets. Cortex is a catalyst for innovation that brings together big-thinking problem solvers with state-of-the-art resources, facilities, and innovative programming to inspire and drive collaboration.

Highlights

Building conference and collaboration spaces
Adjacent garage and surface parking
Plentiful visitor parking

Property Flyers

Amenities

  • Bio-Tech/ Lab Space
  • Courtyard
  • Metro/Subway
  • Security System
  • Signage

Public Transportation

Commuter RailDriveWalkDistance
Cortex Metrolink Station (MetroLink Blue Line - Metro St. Louis) 0 min 2 min 0.1 mi
Cortex Metrolink Station (MetroLink Blue Line - Metro St. Louis) 2 min 3 min 0.2 mi
AirportDriveWalkDistance
St Louis Lambert International 22 min - 12.0 mi
Scott AFB/Midamerica St Louis 44 min - 29.2 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 218
Type: Surface
Included in Rent: Yes
Rebekah Bahn Kingston 314-584-6203 Colliers
Rebekah Bahn Kingston 314-584-6203 Colliers