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4300 Duncan Ave
Saint Louis, MO 63110 Central West End

Rate Upon Request

Office For Lease  •  9,438+ SF

Property Details

  • Property Type Office
  • Year Built 2008
  • Total Building Size 189,841 SF
  • Tenancy Multiple
  • Building Class A
  • Zoning Commercial
59 Transit Score
73 Walk Score

2 Spaces Available

Name Space Use Size Rent Details
2nd Floor Ste 204 Office 9,438 SF Rate Upon Request
  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
4th Floor Ste 400 Office 36,122 SF Rate Upon Request
- Top floor vacancy
- Full floor opportunity
- Excellent existing conditions
- 31 private offices and an IT room
- Building signage opportunity
- Available 5/1/2026

  • Date available: May 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet

Description

Architecturally striking and built to Fortune 500 standards, 4300 Duncan is a future-forward workplace with technology and collaboration at its core. Infused with equal parts productivity and lifestyle, 4300 Duncan is situated at the center of the  Cortex Innovation District; a gravitational hub for top global talent. 

Cortex is a vibrant, 200-acre hub of business, innovation, and technology integrated into St. Louis’ historic Central West End and Forest Park Southeast neighborhoods, surrounded by nationally-ranked universities and medical centers and abundant cultural and recreational assets. Cortex is a catalyst for innovation that brings together big-thinking problem solvers with state-of-the-art resources, facilities, and innovative programming to inspire and drive collaboration.

Highlights

Building conference and collaboration spaces
Adjacent garage and surface parking
Plentiful visitor parking

Property Flyers

Green Rating

LEED Certified

Amenities

  • Bio-Tech/ Lab Space
  • Courtyard
  • Metro/Subway
  • Security System
  • Signage

Public Transportation

Commuter RailDriveWalkDistance
0 min 2 min 0.1 mi
2 min 4 min 0.2 mi
AirportDriveWalkDistance
St Louis Lambert International 22 min - 15.4 mi
Scott AFB/Midamerica St Louis 44 min - 29.1 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 218
Type: Surface
Included in Rent: Yes
Rebekah Bahn Kingston 314-584-6203 Colliers
Rebekah Bahn Kingston 314-584-6203 Colliers