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4001 Main St
Philadelphia, PA 19127 Manayunk

$795 - $1,000 USD/MO

Office For Lease  •  350+ SF

Property Details

  • Property Type Office
  • Year Built 1890
  • Total Building Size 15,624 SF
  • Tenancy Multiple
  • Building Class C
  • Zoning L4
60 Transit Score
60 Walk Score

2 Spaces Available

Name Space Use Size Rent Details
2nd Floor Ste 200 Flex 350 SF $27.26 USD/SF/YR
  • Date available: Oct 2026
  • Lease term: Negotiable
  • Service type: Full Service Gross
  • Space Type: Relet
2nd Floor Ste 201 Office 525 SF $22.86 USD/SF/YR
  • Date available: Now
  • Lease term: Negotiable
  • Service type: Full Service Gross
  • Built out as: Standard Office
  • Space Type: Relet

Description

Located in the heart of Manayunk, 4001 Main Street is a historic Class B office building blending classic architecture with modern upgrades. Built in 1890 and renovated in 2014, the property spans 15,624 SF across three floors and sits on 0.29 acres. With masonry construction, sprinklers, and air conditioning, the building offers a secure and comfortable workspace. Tenancy includes a mix of professional services, healthcare, and creative firms, creating a vibrant business community.

Highlights

Easy access to major roads and public transit
Features 24-hour access and air conditioning
Located in Manayunk, a lively Philadelphia neighborhood
Historic building renovated in 2014

Amenities

  • 24 Hour Access
  • Bus Line
  • Basement
  • Central Heating
  • Air Conditioning

Major Tenants

Tenant SF Occupied Lease End Date
Amee Psychotherapy, LLC
APOP
Busy Bee Transit
CaidBrandCo
Care R Us Home Care Agency, LLC
Commonwealth of Pennsylvania
DesignBlendz
Fettline Enterprises, LLC
Safi Skinsentials
Vexillum Law

Public Transportation

Commuter RailDriveWalkDistance
Wissahickon (R6 - Southeastern Pennsylvania Transportation Authority Regional Rail (SEPTA Regional Rail)) 3 min 12 min 0.6 mi
Manayunk (R6 - Southeastern Pennsylvania Transportation Authority Regional Rail (SEPTA Regional Rail)) 2 min 13 min 0.7 mi
AirportDriveWalkDistance
Philadelphia International 28 min - 15.3 mi
Trenton Mercer 57 min - 32.8 mi
Carrie Sanford 215-482-2110 Gressen Properties LLC
Carrie Sanford 215-482-2110 Gressen Properties LLC