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400 Newport Center Dr
Newport Beach, CA 92660 Newport Center

Rate Upon Request

Medical For Lease  •  994+ SF

Property Details

  • Property Type Medical
  • Year Built 1961
  • Total Building Size 68,000 SF
  • Tenancy Multiple
  • Building Class B
  • Zoning PC 28
40 Transit Score
80 Walk Score

4 Spaces Available

Name Space Use Size Rent Details
1st Floor Ste 106 Medical 994 SF Rate Upon Request 
Medical space available. Call to show.

  • Date available: 90 Days
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Medical
  • Space Type: Relet
2nd Floor Ste 210 Medical 1,488 SF Rate Upon Request 
Medical space available. Call to show.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Medical
  • Space Type: Relet
4th Floor Ste 401 Medical 3,179 SF Rate Upon Request
  • Date available: May 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
6th Floor Ste 604 Medical 2,576 SF Rate Upon Request 
Medical space available. Call to show.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: Utilities And Char
  • Built out as: Healthcare
  • Space Type: Relet

Description 

400 Newport Center Drive, also known as Newport Center Medical Plaza, offers a premier medical office environment in the heart of Newport Beach’s prestigious business district. This multi-tenant property provides a professional setting with modernized interiors and flexible suite configurations designed to accommodate a range of healthcare and office users.
The building features convenient surface parking, elevator service, and a well-maintained common area, ensuring ease of access for patients and staff. Located within the sought-after Newport Center area, the property is surrounded by high-end retail, dining, and hospitality options, including Fashion Island, and offers quick connectivity to Pacific Coast Highway, the 73 Toll Road, and major freeways.
With its prime location, professional management, and proximity to John Wayne Airport, 400 Newport Center Drive is an exceptional choice for medical practitioners and businesses seeking a high-profile address in Orange County.

Highlights

Convenient access to Pacific Coast Highway, 73 Toll Road, and Interstates 405 and 55.

Property Flyers

Amenities

  • Restaurant
  • Signage
  • Wheelchair Accessible
  • Central Heating
  • Recessed Lighting
  • Outdoor Seating
  • Air Conditioning
  • Smoke Detector

Major Tenants

Tenant SF Occupied Lease End Date
Allergy & Asthma Adults Children
Arthur J Helliwell Inc
Bruce R. Harkins, D.D.S. 9/30/2004
Health Mart Pharmacy
Hersch Pediatric Dentistry
Jon M Grazer, MD, MPH, Inc.
Newport Center Medical Group
Randall Perkins, D.D.S.
United Medical Doctors
West Dermatology-Newport Beach

Public Transportation

Commuter RailDriveWalkDistance
Tustin (Inland Empire-Orange County Line - Southern California Regional Rail Authority (Metrolink), Orange County Line - Southern California Regional Rail Authority (Metrolink)) 14 min - 8.8 mi
AirportDriveWalkDistance
John Wayne/Orange County 11 min - 6.4 mi
Long Beach (Daugherty Field) 33 min - 26.4 mi
Ontario International 60 min - 42.5 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 28
Type: Surface
Included in Rent: Yes
John Scruggs 949-842-5897 CBRE
John Scruggs 949-842-5897 CBRE