Affordable Office / Flex Space Near Downtown St. Petersburg | 1,000–4,600 SF | Flexible Layouts / Suites
For Lease – General Office | Medical | Professional | Contractor Yard + Office Combo with parking
Contractors - Great spot close to permit offices downtown and includes HUGE fenced lot perfect for parking trucks, trailers and other equipment or daily dispatch operations in rare downtown St. Petersburg location.
Well-located commercial space just minutes from Downtown St. Petersburg and major corridors. Ideal for office, medical, and service-oriented tenants seeking affordability, accessibility, and flexible layouts in a central Pinellas County location.
Available Space
1,000 – 4,600 SF (divisible)
Multiple suite configurations
Move-in ready or customizable
Ideal Uses:
Contractors, roofers, plumbers, pest control company electricians great spot to store supplies with huge lot for parking equipment and trucks
Medical: primary care, behavioral health, counseling, PT/rehab, outpatient services
Professional: law firm, CPA, insurance, consulting
Government / nonprofit / social services
Administrative / back-office operations
Education, training, or appointment-based services
Temporary Housing with showers
Property Features
Flexible floor plans (private offices, open workspace, medical layouts)
Ample on-site parking
Easy access to Interstate 275, U.S. Route 19, and downtown
Strong daytime population and workforce density
Cost-effective alternative to Downtown and Central Avenue office space
Exterior signage opportunities
Location Advantages
Central St. Petersburg location with convenient ingress/egress
Minutes to Downtown, hospitals, and business districts
Consistent daytime traffic and visibility
Well-suited for appointment-based, referral-driven, and office users
Lease Highlights
Competitive lease rates (call for details)
Flexible lease terms
Tenant improvement packages available
Contact for pricing, floor plans, and tour availability.
Great Fit for:
Primary care
Community health clinics
Federally Qualified Health Centers (FQHCs)
Infectious disease clinics
Chronic care (diabetes, HIV, wound care)
Behavioral Health / Mental Health Providers
Social services
Veteran services
Housing authority offices
Counseling centers
Psychiatry
Substance use treatment (outpatient)
Case management
Two adjacent vacant lots provide significant value-add potential. One lot has been graveled for immediate parking use, while the second offers the opportunity for fencing or specialized outdoor space, ideal for veterinary or wellness practices. The location benefits from strong visibility and accessibility, with proximity to major thoroughfares, including Interstates 375 and 275, public transit, and walkable downtown amenities.
With its strategic location, modernized infrastructure, and value-add optionality, 400 15th Street N is well-positioned for long-term value in St. Petersburg’s growing medical and professional services market.
Mike Hooper
Rent the Bay