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335 First Ave
New York, NY 10003 Gramercy Park

$15,000 USD/MO

Apartments For Lease  •  1,500 SF

Property Details

  • Property Type Apartments
  • Year Built 1920
  • Total Building Size 5,050 SF
  • Building Class C
  • Zoning C1-6A
100 Transit Score
98 Walk Score

1 Space Available

Name Space Use Size Rent Details
1st Floor Ste Retail 1,500 SF $120.00 USD/SF/YR
Positioned in Gramercy Park along one of Manhattan’s busiest thoroughfares, this ground-floor location offers outstanding street exposure and consistent foot traffic in a multifamily mid-rise building built in 1920. 

Key Features
Approximately 1500SF of space
Former medical office build-out with reception, exam rooms, and support spaces 
Excellent frontage and visibility on 1st Avenue
Located steps from Mount Sinai Beth Israel and Bellevue Hospital—ideal for healthcare or wellness use 
Surrounded by dense residential buildings, boutique retail, cafes, and high pedestrian traffic
High ceilings, bright and open layout with large display windows
Space previously fitted with multiple exam/treatment rooms, a reception/waiting area, private office, and built-in plumbing and ventilation
Zoned C1-6A, suitable for medical, retail, office, or wellness tenants 

Prior Setup Highlights
Reception/Waiting Area oriented toward the storefront
At least two exam or treatment rooms, with plumbing connections available
A private office/back room or staff area
Separate support space for storage or records
Central HVAC and proper ventilation suitable for medical or wellness operations

The layout facilitates a smooth transition for tenants seeking medical, dental, aesthetic, or therapy-related services

Location Benefits
Walking distance to Union Square, local parks, and dynamic East Village amenities—ensuring consistent visibility and foot traffic
Public transit access includes nearby subway lines and multiple bus routes
Surrounded by a vibrant residential and professional tenant base (e.g. NYU, Stuyvesant Town, hospitals) with above-average walk and transit scores 

This space represents a rare opportunity to occupy a fully built-out commercial suite in a highly trafficked, mixed-use mid-rise building. Previously outfitted for medical use with exam rooms, reception, private office, and infrastructure in place, it offers immediate potential for practitioners, wellness brands, or boutique services.

Available Immediately for Lease. Contact today to schedule a tour, review floor plans, or learn about rent and terms.

  • Date available: Now
  • Lease term: 5 - 10 Years
  • Service type: Triple Net
  • Built out as: Specialty
  • Space Type: Relet

Description

Exceptional ground-floor retail opportunity with expansive glass frontage in a high-visibility corner location at East 20th Street and First Avenue.

The Space: Approximately 76 ft x 17 ft (SEE FLOORPLAN) with a large basement, suitable for most dry uses. The unit can be delivered as-is including existing built-in offices OR be delivered vanilla box throughout offering flexibility for a variety of layouts and business types.

Ideal Uses:  Medical office, spa, nail salon, pet grooming, or other retail and service-oriented concepts.

The Location: Situated in the heart of Manhattan’s vibrant East Village, this retail space at 335 First Avenue benefits from excellent foot traffic and strong neighborhood demand. Just steps from Stuyvesant Town and Union Square, the area is surrounded by dense residential buildings, medical offices, restaurants, cafés, and boutique retailers—making it an ideal destination for both local and commuter-driven clientele.

Highlights

High-traffic First Avenue location with strong daily pedestrian volume.
Surrounded by major residential density near Stuyvesant Town and Gramercy.
Close proximity to NYU, Union Square, and Mount Sinai Beth Israel.
Reliable transit access via the First Avenue L train and multiple bus routes.
Ideal corridor for neighborhood retail, medical, and service operators.

Public Transportation

Commuter RailDriveWalkDistance
23 St (PATH) (Hoboken-33rd Street - Port Authority Trans-Hudson (PATH), Journal Square-33rd Street - Port Authority Trans-Hudson (PATH)) 3 min 19 min 1.0 mi
14 St (PATH) (Hoboken-33rd Street - Port Authority Trans-Hudson (PATH), Journal Square-33rd Street - Port Authority Trans-Hudson (PATH)) 4 min - 1.2 mi
Transit/SubwayDriveWalkDistance
1 Avenue (L - New York MTA Subway (The Subway)) 3 min 5 min 0.3 mi
3 Avenue (L - New York MTA Subway (The Subway)) 2 min 10 min 0.5 mi
23 Street (4,6 Line) (4 - New York MTA Subway (The Subway), 6 - New York MTA Subway (The Subway)) 2 min 12 min 0.6 mi
14 Street-Union Square (4 - New York MTA Subway (The Subway), 5 - New York MTA Subway (The Subway), 6 - New York MTA Subway (The Subway), L - New York MTA Subway (The Subway), N - New York MTA Subway (The Subway), Q - New York MTA Subway (The Subway), R - New York MTA Subway (The Subway)) 3 min 13 min 0.7 mi
28 Street (4,6 Line) (4 - New York MTA Subway (The Subway), 6 - New York MTA Subway (The Subway)) 4 min 17 min 0.9 mi
AirportDriveWalkDistance
LaGuardia 19 min - 8.9 mi
Newark Liberty International 25 min - 16.0 mi
John F Kennedy International 27 min - 17.0 mi
Tal Grafi 917-943-5222 Grafi Realty
Tal Grafi 917-943-5222 Grafi Realty