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324 W 125th St
New York, NY 10027 Central Harlem

Rate Upon Request

Storefront For Lease  •  6,780 SF

Property Details

  • Property Type Storefront
  • Year Built 2019
  • Total Building Size 17,384 SF
  • Tenancy Multiple
  • Building Class A
  • Zoning C4-4D
100 Transit Score
100 Walk Score

1 Space Available

Name Space Use Size Rent Details
2nd Floor Ste Medical Office 6,780 SF Rate Upon Request
Prime Medical or Professional Office Sublease – East Harlem
Incredible sublease opportunity in the heart of East Harlem. This second-floor office space is prominently
located on a highly visible corner of East 125th Street, directly above CVS. +/- 6,780 SF Prime Medical or
Professional office space in move in condition. 
With elevator access and excellent street presence, the space is ideal for any medical, dental, or professional
office use.
Twelve (12) years remain on a twenty (20) year lease, offering long-term stability. The former tenant is highly
motivated to make a deal—perfect for a growing practice or business seeking a turnkey location in a vibrant,
high-traffic corridor. Owner is willing to negotiate terms and pricing for the right tenant.

  • Date available: 30 Days
  • Lease term: None
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Sublet

Description

All Showing Requests to Ozie Farrell. MOBILE: 347.920.6079. This ±6,780 SF second-floor suite sits on a highly visible corner along East 125th Street directly above CVS, offering strong street presence and elevator access. The space had previously operated as a restaurant and was fully zoned for medical use when the building was taken over. No
imaging equipment remains, allowing a new operator to design and install systems tailored to their specialty. With a properly managed radiology practice capable of handling an estimated 275 to 375 patients per day, the location offers significant potential for high-volume outpatient services. 
The office is supported by a 3000A, 120/208 volt, 3-phase, 4-wire underground electrical service, suitable for imaging, diagnostics, and other power-intensive medical uses. This sublease presents a rare opportunity for any medical, dental, or professional practice seeking to expand its presence in an under-served uptown community.  
The location provides immediate access to a dense patient base and allows full control over clinical expansion and outpatient footprint. With twelve years remaining on a twenty-year master lease, the space offers long-term stability along with a flexible lease structure and favorable terms. Ownership is motivated and open to negotiation for the right tenant. The surrounding area is anchored by national retailers, community services, and major transit options, including nearby express trains, creating exceptional visibility, accessibility, and patient convenience. This turnkey suite is ideal for a practice looking to grow, strengthen its outpatient operations, or establish a flagship uptown location in a vibrant,high-traffic corridor.

Highlights

All Showing Requests to Ozie Farrell. MOBILE: 347.920.6079
3000A, 120/208V, 3-phase electrical service suitable for imaging and high-intensity clinical operations
Strong outpatient demand in an under-served uptown market, with radiology throughput potential estimated at 275–375 patients per day
Twelve years remaining on a twenty-year master lease and ownership willing to structure favorable sublease term
Highly accessible location near express trains and major transit corridors, offering exceptional visibility and connectivity for patients + staff

Property Flyers

Major Tenants

Tenant SF Occupied Lease End Date
CVS Pharmacy 7/1/2038

Public Transportation

Commuter RailDriveWalkDistance
Harlem-125th Street Station (Harlem Line - Metro-North Commuter Railroad Company (Metro-North), Hudson Line - Metro-North Commuter Railroad Company (Metro-North), New Haven Line - Metro-North Commuter Railroad Company (Metro-North)) 2 min 16 min 0.8 mi
Yankees-E 153rd Street Station (Hudson Line - Metro-North Commuter Railroad Company (Metro-North)) 6 min - 2.4 mi
Transit/SubwayDriveWalkDistance
125 Street (A,B,C,D Line) (A - New York MTA Subway (The Subway), B - New York MTA Subway (The Subway), C - New York MTA Subway (The Subway), D - New York MTA Subway (The Subway)) 0 min 2 min 0.1 mi
125 Street (2,3 Line) (2 - New York MTA Subway (The Subway), 3 - New York MTA Subway (The Subway)) 1 min 9 min 0.4 mi
116 Street (A,B,C Line) (A - New York MTA Subway (The Subway), B - New York MTA Subway (The Subway), C - New York MTA Subway (The Subway)) 2 min 9 min 0.5 mi
125 Street (1 Line) (1 - New York MTA Subway (The Subway)) 1 min 10 min 0.5 mi
135 Street (A,B,C Line) (A - New York MTA Subway (The Subway), B - New York MTA Subway (The Subway), C - New York MTA Subway (The Subway)) 2 min 11 min 0.5 mi
AirportDriveWalkDistance
LaGuardia 15 min - 6.8 mi
John F Kennedy International 28 min - 18.0 mi
Newark Liberty International 29 min - 23.3 mi
Michael Murphy 631-858-2460 Douglas Elliman Commercial
Michael Murphy 631-858-2460 Douglas Elliman Commercial