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315 N San Saba
San Antonio, TX 78207 Historic San Antonio

Rate Upon Request

Medical For Lease  •  502+ SF

Property Details

  • Property Type Medical
  • Year Built 1986
  • Total Building Size 162,987 SF
  • Tenancy Multiple
  • Building Class A
  • Zoning D
70 Transit Score
60 Walk Score

19 Spaces Available

Name Space Use Size Rent Details
1st Floor Ste 100 Office 2,896 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste 101 Office 5,739 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste 103 Office 4,545 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste 107 Office 4,220 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste 110 Office 1,512 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
2nd Floor Ste 201 Office 5,050 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
2nd Floor Ste 203 Office 502 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
9th Floor Ste 910 Office 1,612 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
10th Floor Ste 1003 Office 8,650 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
10th Floor Ste 1061 Office 2,640 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
10th Floor Ste 1065 Office 2,899 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
10th Floor Ste 1070 Office 1,883 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
10th Floor Ste 1075 Office 8,501 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
11st Floor Ste 1175 Office 2,371 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
12nd Floor Ste 1220 Office 3,128 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
12nd Floor Ste 1235 Office 1,251 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
12nd Floor Ste 1240 Office 2,063 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
12nd Floor Ste 1245 Office 1,655 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
12nd Floor Ste 1295 Office 8,092 SF Rate Upon Request
Santa Rosa Pavilion presents a premier medical office leasing opportunity in the center of downtown San Antonio, situated on the campus of the renowned Children’s Hospital of San Antonio. This twelve-story Class A property offers an exceptionally connected location with unmatched access to nearby medical services. Tenants benefit from an enclosed skybridge providing direct connectivity to the hospital—ideal for healthcare professionals seeking efficiency and continuity of care.
The building boasts a fully renovated lobby, modernized elevators, and well-designed common areas that create a professional environment for practitioners and visitors alike. Parking convenience is ensured with a secure, on-campus parking garage, complemented by abundant nearby amenities including Market Square, Milam Park, and San Pedro Creek. An on-site pharmacy and ready-to-occupy suites further enhance functionality for medical practices looking to optimize operations within a walkable downtown location.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet

Description

A twelve-story, 162,987 SF Class A medical office building positioned in San Antonio’s central business district on the Children’s Hospital campus. The property includes an on-site pharmacy, enclosed pedestrian skybridge to the hospital, and secured on-campus parking garage. Nearby attractions include San Pedro Creek, Milam Park, and Historic Market Square. Public transportation and major roadways are easily accessible.

Highlights

Direct access to The Children’s Hospital of San Antonio via enclosed skybridge.
Fully renovated common areas and contemporary lobby design.
Convenient on-site pharmacy located within the building.
Secure parking garage available on campus for tenants and patients.
Proximity to downtown amenities, dining, and cultural attractions.
Customizable suites with second-generation and move-in ready options.

Property Flyers

Amenities

  • 24 Hour Access
  • Bus Line
  • Property Manager on Site
  • Restaurant
  • Signage

Major Tenants

Tenant SF Occupied Lease End Date
CHRISTUS Health
DM Clinical Research
Lifecare Pharmacy
Northeast Children's Dentistry
Providence Health & Services
Retina Associates Of S Texas 11/6/2028
Sng San Saba
The Center for Health Care Services 10/31/2026
Westover Hills Women's Health 10/7/2016

Public Transportation

Commuter RailDriveWalkDistance
5 min - 2.1 mi
AirportDriveWalkDistance
San Antonio International 13 min - 7.9 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 100
Type: Surface
Included in Rent: Yes
Chad Gunter 210-366-2222 Endura Advisory Group
Chad Gunter 210-366-2222 Endura Advisory Group