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311 Arsenal St
Watertown, MA 02472 East Watertown

Rate Upon Request

Unknown For Lease  •  3,530+ SF

Property Details

  • Property Type Unknown
  • Year Built 1917
50 Transit Score
70 Walk Score

21 Spaces Available

Name Space Use Size Rent Details
1st Floor Ste Office 8,850 SF Rate Upon Request 
500 North Beacon Street celebrates the rich history of the campus while injecting the site with a contemporary aesthetic. The new office and research laboratory facility, which is targeting LEED Gold and Fitwel certifications, consists of two main volumes: a four-story structure clad in vertical copper fins and a lower glass volume featuring a large fourth floor terrace.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet
1st Floor Ste Office 24,885 SF Rate Upon Request 
Bio-Tech / Lab Space available for lease

  • Date available: Now
  • Lease term: Negotiable
  • Service type: Negotiable
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste Office 39,921 SF Rate Upon Request 
Bio-Tech / Lab Space available for lease

  • Date available: Now
  • Lease term: Negotiable
  • Service type: Negotiable
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste Office 8,033 SF Rate Upon Request 
This 8,033 SF office and lab suite within a dynamic life sciences campus in Watertown, MA. This thoughtfully designed space combines workplace flexibility with specialized laboratory capabilities to support research-focused teams. The suite features 23 workstations, 2 private offices, 1 conference room, a huddle room, phone room, dedicated lab office, and a break room.
Laboratory accommodations include 20 open lab benches, 2 tissue culture labs, and a glass wash/equipment room, making it ideal for emerging biotech and life sciences users. Common amenities include a 30-person seminar/conference room and a café with 12-person seating, promoting collaboration and community engagement.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: Negotiable
  • Built out as: Standard Office
  • Space Type: Relet
1st Floor Ste 1E Office 9,211 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
1st Floor Ste 1E Office 5,781 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
1st Floor Ste 1W Office 15,795 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
1st Floor Ste 1W Office 24,605 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
2nd Floor Ste Office 7,588 SF Rate Upon Request 
This 7,588 SF lab and office suite designed for growing life sciences and research organizations. Situated within a redeveloped campus in Watertown, this space offers a balanced program of collaborative and specialized environments. The layout includes 24 workstations, 2 private offices, a conference room, a huddle room, phone room, dedicated lab office, and a break room.

The laboratory area is equipped with 20 open lab benches, 2 tissue culture labs, and a glass wash/equipment room to support diverse research workflows. Tenants enjoy access to shared building amenities, including a seminar/conference room accommodating up to 30 attendees and a café on Level 2 for informal gatherings.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Research And Development
  • Space Type: Relet
2nd Floor Ste Office 5,374 SF Rate Upon Request 
This 5,374 SF lab and office suite purposefully designed to accommodate research and collaboration within a premier life sciences campus. This thoughtfully configured suite features 12 workstations, 1 private office, and 2 conference rooms to support team meetings and executive functions.

The laboratory environment provides 18 open lab benches, 2 tissue culture labs, a dedicated glass wash room, and a freezer room, ensuring critical infrastructure is in place for specialized research needs. Tenants will also benefit from the larger campus experience, including modern fitness facilities, childcare services, communal lounges, and nearby dining and retail at Arsenal Yards.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Research And Development
  • Space Type: Relet
2nd Floor Ste 2E Office 4,287 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
2nd Floor Ste 2W Office 27,278 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
3rd Floor Ste Office 11,067 SF Rate Upon Request 
This 11,067 SF office suite tailored for teams seeking an upscale, collaborative environment within a full-service life sciences and office campus. This thoughtfully planned suite includes 13 workstations, 22 private offices for executive and focused work, and 2 well-equipped conference rooms for group collaboration. Enhancing the space are premium tenant amenities such as a dedicated fitness center and a café-style coffee bar within the suite itself, promoting wellness and convenience for daily operations.

  • Date available: Mar 2027
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
3rd Floor Ste 3W Office 21,579 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
3rd Floor Ste MEZZ (EAST) Office 3,530 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
4th Floor Ste Office 21,531 SF Rate Upon Request 
This 21,531 SF lab/office suite configured to meet the needs of advanced research operations within a world-class life sciences campus. This expansive workspace includes 12 workstations and 18 private offices for focused productivity, complemented by 3 conference rooms and 2 collaborative rooms to support team engagement. A dedicated in-suite cafeteria provides convenience for staff and visitors.

Laboratory infrastructure is robust, featuring a biology lab, biological analytical lab, chemistry lab, two tissue culture labs, cold room, glass wash area, and freezer room. These purpose-built areas provide scalable, turnkey solutions for biotech firms and R&D-driven organizations needing integrated lab and office capabilities.

  • Date available: Mar 2027
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Research And Development
  • Space Type: Relet
4th Floor Ste 4E Office 29,262 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
4th Floor Ste 4W Office 31,570 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
5th Floor Ste Office 21,531 SF Rate Upon Request 
21,531 SF office suite designed for corporate, research, or hybrid workplace teams seeking a high-capacity layout supported by modern amenities. This suite offers 32 workstations and 43 private offices, providing ample dedicated spaces for leaders and team members. Collaboration is supported through 2 conference rooms, 1 board room, 2 collaboration rooms, and 1 huddle room, creating a diverse mix of formal and informal meeting areas.

Additional in-suite amenities include 5 phone rooms, a coffee bar, a dedicated security office, and a wellness room, allowing companies to promote comfort, privacy, and well-being within the workplace.

  • Date available: Mar 2027
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
5th Floor Ste 5E Office 5,820 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF
5th Floor Ste 5W Office 31,548 SF Rate Upon Request 
Modern office and lab-ready suites located within an amenity-rich, sustainability-focused campus. Flexible layouts designed to accommodate both creative office users and advanced life sciences operations. Immediate access to retail, dining, and major transportation routes ensures convenience for employees and visitors.

  • Date available: Now
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Built out as: Standard Office
  • Space Type: Relet
  • In Contiguous block: 210,266 SF

Description 

The Arsenal on the Charles offers an exceptional opportunity to lease office and life sciences space within a transformative campus environment in East Watertown. Boasting a mix of history and innovation, this dynamic 59-acre campus is designed for collaboration and connectivity. Tenants benefit from access to an impressive amenity package, including a full-service fitness center, childcare facilities, dining options, and green spaces that enhance workplace well-being.

The campus stands at the heart of a thriving commercial corridor adjacent to Arsenal Yards, providing immediate access to retail, dining, and entertainment options. Commuters will appreciate excellent regional connectivity via Arsenal Street, which links directly to the Massachusetts Turnpike (I-90) and offers easy access to Cambridge, Boston, and surrounding innovation clusters. The property is also well-served by MBTA bus routes, with convenient proximity to major employment and residential hubs.

With flexible floor plans and brand-new laboratory and office configurations targeting LEED Gold and Fitwel certifications, this campus offers a forward-thinking environment ideal for cutting-edge research, technology, and creative office users seeking scalable, sustainable space.

Highlights

Amenity-rich campus featuring fitness center, childcare, collaboration areas, and green outdoor spaces.
Direct access to Arsenal Street with connectivity to I-90, Cambridge, and Boston’s innovation corridor.
On-campus community anchored by modernized spaces and proximity to Arsenal Yards dining and retail.
Flexibility to accommodate office and life science users with customizable layouts and advanced building systems.
Contemporary renovations aimed at achieving LEED Gold and Fitwel sustainability certifications.

Property Flyers

Amenities

  • Courtyard
  • Wheelchair Accessible
  • Air Conditioning

Public Transportation

Commuter RailDriveWalkDistance
Newtonville (Framingham/Worcester Line - Massachusetts Bay Transportation Authority Commuter Rail (Purple Line)) 5 min - 2.7 mi
Waverley (Fitchburg/South Acton Line - Massachusetts Bay Transportation Authority Commuter Rail (Purple Line)) 7 min - 3.0 mi
AirportDriveWalkDistance
General Edward Lawrence Logan International 19 min - 10.0 mi
Molly Heath 617-316-6489 JLL
Molly Heath 617-316-6489 JLL