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249 E Grand Ave
South San Francisco, CA 94080

Rate Upon Request

Unknown For Lease  •  22,250+ SF

Property Details

  • Property Type Unknown
  • Year Built 2008
0 Transit Score
38 Walk Score

2 Spaces Available

Name Space Use Size Rent Details
2nd Floor Ste Flex 22,250 SF Rate Upon Request 
Lab build out

  • Date available: Sep 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: New
3rd Floor Ste Flex 37,532 SF Rate Upon Request 
Office build out

  • Date available: Sep 2026
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: New

Description 

Join a premier life science campus with the versatile spec suites available for lease at East Grand Avenue in South San Francisco, California. Coming available in September of 2026, these modern spaces include options for 22,250 and 37,532 square feet, offering an ideal canvas for growing teams and institutional businesses. 
 
This incredible business destination offers a range of exceptional on-site amenities that form an idyllic and energizing hub for corporate activity. Tenants enjoy access to an activated wellness center, a restaurant, sports courts, and a 300-person conferencing center. There is also abundant on-site parking available with EV charging stations, as well as generous outdoor space with outdoor walking trails and lush landscaping. 
 
Situated in a prominent location close to the Highway 101 interchange, this rare offer places businesses in an easily accessible commercial hub. The campus is just a short walk to the SSF Caltrain station, and less than 10 minutes from SFO airport. The surrounding area presents a wide array of desirable urban amenities, including top-rated shopping, dining, recreation, and hotels.

Highlights

Versatile spec suites within South San Francisco’s premier life science campus, with space options for 22,250 and 37,532 square feet.
Exceptional amenity package, including an on-site restaurant, an activated wellness center, a conferencing center, and ample parking with EV chargers.
Located minutes from the Highway 101 interchange, walkable from the SSF Caltrain Station and under 10 minutes from San Francisco Intl Airport.
Tenants are placed within minutes of desirable urban amenities, including popular restaurants, retail, hotels, and service-based businesses.

Property Flyers

Major Tenants

Tenant SF Occupied Lease End Date
Bright Horizons
Insitro, Inc. 8/31/2034
Merck 5/1/2034
Molecular Stethoscope
Verily 4/1/2024

Public Transportation

Commuter RailDriveWalkDistance
South San Francisco (Caltrain - Caltrain (Caltrain)) 1 min 11 min 0.5 mi
6 min - 2.3 mi
Transit/SubwayDriveWalkDistance
South San Francisco (Caltrain - Caltrain (Caltrain)) 1 min 11 min 0.5 mi
AirportDriveWalkDistance
San Francisco International 10 min - 4.3 mi
Metro Oakland International 42 min - 28.9 mi
Norman Y Mineta San Jose International 45 min - 36.0 mi
Scott Miller 650-480-2199 JLL
Scott Miller 650-480-2199 JLL