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2480 Mission St
San Francisco, CA 94110 Mission

Rate Upon Request

Medical For Lease • 445+ SF

Property Details

Property Type Medical
Year Built 1972
Total Building Size 36,969 SF
Tenancy Multiple
Building Class B
Zoning NC-3, San Francisco

89 Transit Score

99 Walk Score

14 Spaces Available

Name	Space Use	Size	Rent
1st Floor Ste 104	Medical Office	975 SF	Rate Upon Request
Office Space Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
1st Floor Ste 106	Medical Office	992 SF	Rate Upon Request
office/ Dental/Medical Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
1st Floor Ste 107 A	Medical Office	727 SF	Rate Upon Request
Office Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
1st Floor Ste 107 B	Medical Office	445 SF	Rate Upon Request
Office Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
1st Floor Ste 109	Medical Office	1,054 SF	Rate Upon Request
Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
1st Floor Ste 110	Medical Office	568 SF	Rate Upon Request
office Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet
2nd Floor Ste 212	Medical Office	2,854 SF	Rate Upon Request
Beautifully remodeled, ready. Date available: Now Lease term: Negotiable Service type: Triple Net Built out as: Standard Office Space Type: Relet
2nd Floor Ste 214	Medical Office	1,109 SF	Rate Upon Request
1,109 square foot office/medical space along with a mix of private offices available. Complete 2 dental opt plumbing in place. Tenant improvement help available. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
2nd Floor Ste 216	Medical Office	1,129 SF	Rate Upon Request
1,129 square foot office/medical space along with a mix of private offices available. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Medical Space Type: Relet
2nd Floor Ste 217	Medical Office	1,009 SF	Rate Upon Request
1,009 square foot office/medical space along with a mix of private offices available. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Dental Space Type: Relet
2nd Floor Ste 218-219	Medical Office	2,548 SF	Rate Upon Request
2,548 square foot office/medical space along with a mix of private offices available. Complete 4 dental opts plumbing in place. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Dental Space Type: Relet
2nd Floor Ste 220	Medical Office	1,176 SF	Rate Upon Request
1,176 square foot office/medical space along with a mix of private offices available. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Dental Space Type: Relet
2nd Floor Ste 221	Medical Office	918 SF	Rate Upon Request
918 square foot office/medical space along with a mix of private offices available. Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Dental Space Type: Relet
2nd Floor Ste 222	Medical Office	926 SF	Rate Upon Request
Date available: Now Lease term: Negotiable Service type: To Be Determined Built out as: Standard Office Space Type: Relet

Description

LOS PORTALES CENTER, 2480 Mission Street

Nestled in San Francisco’s lively Mission District. Discover one of the neighborhood’s premier destinations for professional office spaces. This well-maintained property offers a range of suites from 445 SF to 2,845 SF, with the flexibility to merge units to fit your growing business needs.
Enjoy a professional and welcoming environment ideal for startups, professional services, medical and dental practices, beauty and wellness providers, and various therapy practices. Single occupants and group tenants are both welcome.
Property Highlights:

•	Flexible lease terms at competitive rates
•	Secure on-site parking garage with convenient tenant access
•	Easy access to public transportation
•	Surrounded by top local amenities, including Grand Coffee, Lolinda, and Foreign Cinema
•	Open Monday through Saturday

Grow your business in a space that combines comfort, convenience, and professionalism—perfectly positioned in one of the city’s most vibrant neighborhoods.

                
                    Highlights
                
                                Premier office Building in the heart of the Mission District
                            
                                Excellent public transportation - Muni and BART (24th & Mission)
                            
                                Tenants' onsite parking garage
                            
                                Elevator served

Property Flyers

2480 Mission Street-Dec-2025-2

Amenities

24 Hour Access
Wheelchair Accessible
Roof Terrace

Public Transportation

Commuter Rail	Drive	Walk	Distance
San Francisco 4th & King (Caltrain - Caltrain (Caltrain))	6 min	-	2.5 mi
	7 min	-	2.6 mi
Transit/Subway	Drive	Walk	Distance
24th St Mission Station (Dublin/Pleasanton - Millbrae - Bay Area Rapid Transit (BART), Fremont - Daly City - Bay Area Rapid Transit (BART), Pittsburg/Bay Point - San Francisco International - Bay Area Rapid Transit (BART), Richmond - Millbrae - Bay Area Rapid Transit (BART))	3 min	8 min	0.4 mi
21st Street (J Church - San Francisco Municipal Railway (MUNI Metro))	3 min	9 min	0.4 mi
Liberty Street (J Church - San Francisco Municipal Railway (MUNI Metro))	3 min	9 min	0.5 mi
Church and 18th Street (J Church - San Francisco Municipal Railway (MUNI Metro))	2 min	14 min	0.7 mi
Airport	Drive	Walk	Distance
San Francisco International	22 min	-	12.5 mi
Metro Oakland International	34 min	-	21.1 mi
Norman Y Mineta San Jose International	58 min	-	44.1 mi

Parking Details

Parking Available:	Yes
Reserved:	No
Type:	SurfaceTandem
Included in Rent:	Yes

Manaf Darawshe 650-533-8036 Starboard Commercial Real Estate

2480 Mission St San Francisco, CA 94110 Mission