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22 S Main St
Greenville, SC 29601 West Downtown

Rate Upon Request

Office For Lease  •  8,500 SF

Property Details

  • Property Type Office
  • Year Built 2011
  • Total Building Size 41,494 SF
  • Tenancy Multiple
  • Building Class B
  • Zoning MXS-D
40 Transit Score
90 Walk Score

1 Space Available

Name Space Use Size Rent Details
1st Floor Ste Retail 8,500 SF Rate Upon Request
±8,500 SF Main Street retail space for lease (available Feb. 2027)
Located in the center of Downtown Greenville across from the Wells Fargo Tower

  • Date available: Feb 2027
  • Lease term: Negotiable
  • Service type: To Be Determined
  • Space Type: Relet

Description

Position your business in the heart of Downtown Greenville with this exceptional retail opportunity at 22 S. Main Street. Offering approximately 8,500 SF of prime ground-floor space, this property is ideally situated along Greenville’s most vibrant retail corridor, directly across from the Wells Fargo Tower. A new façade renovation is underway, ensuring a modern and inviting storefront that will enhance visibility and curb appeal for future tenants.
The property benefits from heavy pedestrian and vehicular traffic, with Main Street seeing over 7,200 vehicles per day and McBee Avenue over 7,000 VPD. Surrounded by a dynamic mix of national and local retailers, popular restaurants, and entertainment venues, this location offers unmatched exposure and synergy. Nearby establishments include Methodical Coffee, Anthropologie, Tupelo Honey, Cantina 76, and Mast General Store, creating a strong co-tenancy environment.
Downtown Greenville is a thriving destination for residents, visitors, and businesses, with a growing population and robust household incomes averaging over $140,000 within a one-mile radius. The area attracts significant visitor spending, with $793 million allocated to attractions, retail, and entertainment annually. This property is perfectly positioned to capture that demand, making it an ideal choice for flagship retail, experiential concepts, or destination dining.

Highlights

Prime Main Street location in the center of Downtown Greenville’s retail and dining district
New façade renovation planned to enhance visibility and modernize the storefront
Surrounded by top-tier retailers and restaurants, including Anthropologie, Tupelo Honey, and Mast General Store
Strong demographics with high household incomes and significant visitor spending in the area
Excellent traffic counts with over 7,200 vehicles per day on Main Street

Property Flyers

Major Tenants

Tenant SF Occupied Lease End Date
Lincoln Energy Solutions
Nexus Program Management Group, LLC
Team Logistics Company LLC

Public Transportation

Commuter RailDriveWalkDistance
3 min 20 min 1.0 mi
AirportDriveWalkDistance
Greenville Spartanburg International 21 min - 14.3 mi

Parking Details

Parking Available: Yes
Reserved: No
Spaces Provided: 3
Type: Surface
Included in Rent: Yes
Cortney Carter 864-752-0302 Collett & Associates
Cortney Carter 864-752-0302 Collett & Associates