112 E Main St
Barstow, CA 92311

112 E Main Street (Historic Route 66) offers a rare opportunity to acquire a highly visible commercial development site in the heart of Barstow. The property is comprised of 8 contiguous parcels totaling approximately 97,500 square feet (±2.24 acres). Previously operated as a motel, the site now presents a blank canvas for a wide range of commercial development opportunities.

With prominent frontage along Historic Route 66 (E Main Street), as well as additional frontage and access from S 2nd Avenue and East Williams Street, the property benefits from excellent ingress, egress, and exposure to local and regional traffic. Zoned Commercial, the site allows for a variety of potential uses including self-storage, retail, service commercial, automotive, and mixed-use projects. The property is strategically located near major transportation corridors including I-15 and I-40, providing strong connectivity to regional logistics, tourism, and growing economic activity throughout Barstow and the surrounding High Desert region.